Antonio Jiménez Ruiz

Artículos

• HENR??QUEZ FIGUEREO, Andreina; ALC??N CALDER??N, Mar??a de las Mercedes; MORENO AMATRIA, Esther; SANMART??N GRIJALBA, Carmen; ESPUELAS MILL??N, Mar??a Socorro; LUCIO ORTEGA, H??ctor Elessar de; JIM??NEZ RUIZ, Antonio; PLANO AMATRIAIN, Daniel; ."Next generation of selenocyanate and diselenides with upgraded leishmanicidal activity". (ISSN: 0045-2068). Bioorganic Chemistry. 2023 , vol 138 , num 106624 , p. 1 - 12 .  .

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• A. MESA-ARANGO, Jairo; M. OLAVE-VELANDIA, Ana; M. GARC??A-MONTOYA, Gisela; P. ISAZA-AGUADO, Juan; JIM??NEZ RUIZ, Antonio; F. ALZATE, Juan; ."Evaluation of new Toxocara canis chimeric antigens as an alternative to conventional TES-Ag for anti-Toxocara antibodies detection". Heliyon. 2022 , vol 8 , num 10 , p. 1 - 15 .  .

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• LUCIO ORTEGA, H??ctor Elessar de; GARC??A MARIN, Javier; S??NCHEZ ALONSO, Patricia; GARC??A SORIANO, Juan Carlos; TORO LONDO??O, Miguel; VAQUERO L??PEZ, Juan Jos??; GAGO BADENAS, Federico; ALAJAR??N FERR??NDEZ, Luis Ram??n; JIM??NEZ RUIZ, Antonio; ."Pyridazino-pyrrolo-quinoxalinium salts as highly potent and selective leishmanicidal agents targeting trypanothione reductase". (ISSN: 0223-5234). European Journal of Medicinal Chemistry. 2022 , vol 227 , num 113915 , p. 1 - 13 .  .

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• ETXEBESTE-MITXELTORENA , Mikel; PLANO , D; ESPUELAS , Socoro; MORENO , Esther; AYDILLO , Carlos; JIM??NEZ RUIZ, Antonio; GARC??A-SORIANO , Juan Carlos; SANMART??N , Carmen; ."New phosphoramidates containing selenium as leishmanicidal agents". (ISSN: 0066-4804). Antimicrobial Agents and Chemotherapy. 2021 , vol 65 , num 10 , p. 1 - 13 .

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• REVUELTO , Alejandro; DE LUCIO , H??ctor; GARC??A SORIANO, Juan Carlos; S??NCHEZ-MURCIA , Pedro A.; GAGO BADENAS, Federico; JIM??NEZ RUIZ, Antonio; CAMARASA RIUS, Mar??a Jos??; VEL??ZQUEZ , Sonsoles; ."Efficient Dimerization Disruption of Leishmania infantum Trypanothione Reductase by Triazole-phenyl-thiazoles". (ISSN: 0022-2623). Journal of Medicinal Chemistry. 2021 , vol 64 , num 9 , p. 6137 - 6160 .

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• ALCOLEA , Veronica; MORENO , Esther; ETXEBESTE-MITXELTORENA , Mikel; NAVARRO-BLASCO , Inigo; GONZALEZ-PENAS , Elena; JIM??NEZ RUIZ, Antonio; IRACHE , Juan Manuel; SANMARTIN , Carmen; ESPUELAS , Socorro; ."3,5-Dimethyl-4-isoxazoyl selenocyanate as promising agent for the treatment of Leishmania infantum-infected mice". (ISSN: 0001-706X). Acta Tropica. 2021 , vol 215 , num 105801 , p. 1 - 8 .  .

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• ETXEBESTE-MITXELTORENA , Mikel; PLANO , Daniel; ESPUELAS , Socorro; MORENO , Esther; AYDILLO , Carlos; JIM??NEZ RUIZ, Antonio; GARCIA SORIANO , Juan Carlos; SANMARTIN , Carmen; ."New amides containing selenium as potent leishmanicidal agents targeting trypanothione reductase". (ISSN: 0066-4804). Antimicrobial Agents and Chemotherapy. 2020 , vol 65 , num 1 (e00524-20) .  .

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• LUCIO ORTEGA, H??ctor Elessar de; TORO LONDO??O, Miguel ??ngel; CAMARASA RIUS, Mar??a Jos??; VEL??ZQUEZ D??AZ, Sonsoles; GAGO BADENAS, Federico; JIM??NEZ RUIZ, Antonio; ."Pseudoirreversible slow-binding inhibition of trypanothione reductase by a protein-protein interaction disruptor". (ISSN: 0007-1188). British Journal of Pharmacology. 2020 , vol 177 , num 22 , p. 5163 - 5176 .  .

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• GARNICA , P.; ETXEBESTE MITXELTORENA , Mikel; PLANO , D.; MORENO , E.; ESPUELAS , S.; PALOP , J.A.; JIM??NEZ RUIZ, Antonio; SANMART??N , C.; ."Pre-clinical evidences of the antileishmanial effects of diselenides and selenocyanates". (ISSN: 0960-894X). Bioorganic and Medicinal Chemistry Letters. 2020 , vol 30 , num 17 , p. 1 - 5 .  .

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• LOSADA , Alejandro; BERLANGA , Juan Jos??; MOLINA-GUIJARRO , Jos?? Manuel; JIM??NEZ RUIZ, Antonio; GAGO BADENAS, Federico; AVIL??S MAR??N, Pablo Manuel; DE HARO , C??sar; MART??NEZ LEAL, Juan Fernando; ."Generation of endoplasmic reticulum stress and inhibition of autophagy by plitidepsin induces proteotoxic apoptosis in cancer cells". (ISSN: 0006-2952). Biochemical Pharmacology. 2020 , vol 172 , p. 1137 -

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• REVUELTO , Alejandro; RUIZ-SANTAQUITERIA , Marta; LUCIO ORTEGA, H??ctor Elessar de; GAMO , Ana; CARRILES , Alejandra; GUTIERREZ , Kilian Jes??s; S??NCHEZ MURCIA, Pedro Alejandro; HERMOSO , Juan A.; GAGO BADENAS, Federico; CAMARASA , Mar??a Jos??; JIM??NEZ RUIZ, Antonio; VEL??ZQUEZ , Sonsoles; ."Pyrrolopyrimidine vs Imidazole-Phenyl-Thiazole Scaffolds in Nonpeptidic Dimerization Inhibitors of Leishmania infantum Trypanothione Reductase ". ACS Infectious Diseases. 2019 , vol 5 , num 6 , p. 873 - 891 .  .

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• BRAVO , Ana; LUCIO ORTEGA, H??ctor Elessar de; S??NCHEZ MURCIA, Pedro; JIM??NEZ RUIZ, Antonio; PETRONE , Paula M.; GAGO BADENAS, Federico; CORT??S CABRERA, Alvaro; ."Identification of NEK3 and MOK as novel targets for lithium". (ISSN: 1747-0277). Chemical Biology and Drug Design. 2019 .

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• AL-TAMINI , Abdul-Malek S.; ETXEBESTE-MITXELTORENA , Mikel; SANMART??N , Carmen; JIM??NEZ RUIZ, Antonio; SYRJANEN , Leo; PARKKILA , Seppo; SELLERI , Silvia; CARTA , Fabrizio; ANGELI , Andrea; SUPURAN , Claudiu T.; ."Discovery of new organoselenium compounds as antileishmanial agents". (ISSN: 0045-2068). Bioorganic Chemistry. 2019 , vol 86 , p. 339 - 345 .

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• RUIZ SANTAQUITERIA, Marta; DE CASTRO , Sonia; TORO , Miguel; LUCIO ORTEGA, H??ctor Elessar de; GUTI??RREZ , Kilian Jes??s; S??NCHEZ MURCIA, Pedro; JIM??NEZ , Mar??a ??ngeles; GAGO BADENAS, Federico; JIM??NEZ RUIZ, Antonio; CAMARASA , Mar??a Jos??; VEL??ZQUEZ , Sonsoles; ."Trypanothione reductase inhibition and anti-leishmanial activity of all-hydrocarbon stapled alfa-helical peptides with improved proteolytic stability". (ISSN: 0223-5234). European Journal of Medicinal Chemistry. 2018 , vol 149 , p. 238 - 247 .  .

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• L??PEZ GUTIERREZ, Celia; LUCIO ORTEGA, H??ctor Elessar de; GARC??A SORIANO, Juan Carlos; JIM??NEZ RUIZ, Antonio; ."Introducci??n del sistema CRISPR/Cas9 en Leishmania infantum". Dianas. 2017

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• OLIVA CORREIA, Cristina; S??NCHEZ-MURCIA , Pedro A.; RICO VIDAL, Eva; BRAVO GARC??A, Ana; MEN??NDEZ , Margarita; GAGO BADENAS, Federico; JIM??NEZ RUIZ, Antonio; ."Structure-based domain assignment in Leishmania infantum EndoG: characterization of a pH-dependent regulatory switch and a C-terminal extension that largely dictates DNA substrate preferences.". (ISSN: 0305-1048). Nucleic Acids Research. 2017 , vol 45 , num 15 , p. 9030 - 9045 .

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• RUIZ-SANTAQUITERIA , Marta; S??NCHEZ MURCIA, Pedro Alejandro; TORO , Miguel; DE LUCIO , H??ctor; GUTIERREZ , Kilian Jes??s; DE CASTRO , Sonia; CARNEIRO , Filipa; GAGO BADENAS, Federico; JIM??NEZ RUIZ, Antonio; CAMARASA , Mar??a Jos??; VEL??ZQUEZ , Sonsoles; ."First example of peptides targeting the dimer interface of Leishmania infantum trypanothione reductase with potent in vitro antileishmanial activity". (ISSN: 0223-5234). European Journal of Medicinal Chemistry. 2017 , vol 135 , p. 49 - 59 .

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• MARIO GENES, Carlos; LUCIO ORTEGA, H??ctor Elessar de; MANUEL GONZ??LEZ, V??ctor; S??NCHEZ MURCIA, Pedro Alejandro; RICO , Eva; GAGO BADENAS, Federico; FASEL , Nicholas; JIM??NEZ RUIZ, Antonio; ."A functional BH3 domain in an aquaporin from Leishmania infantum". Cell Death Discovery. 2016 , vol 2 , num 16043 , p. 1 - 10 .  .

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• LUCIO ORTEGA, H??ctor Elessar de; GENES ROBLES, Carlos Mario; S??NCHEZ MURCIA, Pedro; GAGO BADENAS, Federico; JIM??NEZ RUIZ, Antonio; ."Implicaci??n del dominio BH3 de Li-BH3AQP en la muerte celular deL. infantum". Dianas. 2016

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• BAQUEDANO , Ylenia; ALCOLEA , V.; TORO , M.A.; GUTI??RREZ , K.J.; NGUEWA , P.; FONT , M.; MORENO , E.; ESPUELAS , S.; JIM??NEZ RUIZ, Antonio; PALOP , J. A.; PLANO , D.; SANMART??N , C.; ."Novel heteroaryl selenocyanates and diselenides as potent antileishmanial agents.". (ISSN: 0066-4804). Antimicrobial Agents and Chemotherapy. 2016 .

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• , Lopes RM; JIM??NEZ RUIZ, Antonio; , Pereira J; , Esteves MA; , Gaspar MM; , Carvalheiro M; , Eleut??rio CV; , Gon??alves L; , Jim??nez-Ruiz A; , Almeida AJ; , Cruz ME; ."Lipid-based nanoformulations of trifluralin analogs in the management of Leishmania infantum infections.". Nanomedicine (London, England). 2016 , vol 11 , p. 153 - 170

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• S??NCHEZ MURCIA, Pedro; RUIZ SANTAQUITERIA, Marta; TORO , Miguel; LUCIO ORTEGA, H??ctor Elessar de; JIM??NEZ , Mar??a ??ngeles; GAGO BADENAS, Federico; JIM??NEZ RUIZ, Antonio; CAMARASA , Mar??a Jos??; VEL??ZQUEZ , Sonsoles; ."Comparison of hydrocarbon-and lactam-bridged cyclic peptides as dimerization inhibitors of Leishmania infantum trypanothione reductase". (ISSN: 2046-2069). RSC Advances. 2015 .

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• BAQUEDANO , Y.; ESPUELAS , E.; NGUEWA , P.; FONT , M.; GUTIERREZ , K.J.; JIM??NEZ RUIZ, Antonio; PALOP , J. A.; SANMART??N , C.; ."Novel hybrid selenosulfonamides as potent antileishmanial agents". (ISSN: 0223-5234). European Journal of Medicinal Chemistry. 2014 , num 74 , p. 116 - 123 .

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• RICO , E.; GUTIERREZ , K.J.; ALZATE , J.F.; MORENO-MATEOS , D.; GENES , C.M.; CASANOVA , E.; GIGANTE , A.; PEREZ-PEREZ , M.J.; CAMARASA , M.J.; JIM??NEZ RUIZ, Antonio; ."Leishmania infantum EndoG is an endo/exo-nuclease essential for parasite survival". (ISSN: 1932-6203). PLoS ONE. 2014

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• TORO LONDO??O, Miguel ??ngel; S??NCHEZ-MURCIA , Pedro A.; MORENO MATEOS, David; RUIZ-SANTAQUITERIA , Marta; ALZATE RESTREPO, Juan Fernando; NEGRI MART??NEZ, Ana; CAMARASA RIUS, Mar??a Jos??; GAGO BADENAS, Federico; VEL??ZQUEZ , Sonsoles; JIM??NEZ RUIZ, Antonio; S??NCHEZ MURCIA, Pedro Alejandro; ."Probing the Dimerization Interface of Leishmania infantum Trypanothione Reductase with Site-Directed Mutagenesis and Short Peptides". (ISSN: 1439-4227). Chembiochem : a European journal of chemical biology. 2013 , num 4(10) , p. 1212 - 1217 .

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• CASANOVA MALPICA, Elena; MORENO MATEOS, David; GIGANTE MART??NEZ, Alba; RICO VIDAL, Eva; GENES ROBLES, Carlos Mario; OLIVA CORREIA, Cristina; CAMARASA RIUS, Mar??a Jos??; GAGO BADENAS, Federico; JIM??NEZ RUIZ, Antonio; P??REZ P??REZ, M?? Jes??s; ."5'-Trityl-Substituted Thymidine Derivatives as a Novel Class of Antileishmanial Agents: Leishmania infantum EndoG as a Potential Target". (ISSN: 1860-7179). ChemMedChem. 2013 , num 8(7) , p. 1161 - 1174

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• BUEREN CALABUIG, Juan Antonio; CODERCH BOU??, Claire; RICO VIDAL, Eva; JIM??NEZ RUIZ, Antonio; GAGO BADENAS, Federico; ."Mechanistic Insight into the Catalytic Activity of betabetaalfa-Metallonucleases from Computer Simulations: Vibrio vulnificus Periplasmic Nuclease as a Test Case". (ISSN: 1439-4227). Chembiochem : a European journal of chemical biology. 2011 , vol 12(17) , p. 2615 - 2622

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• PLANO , D; BAQUEDANO , Ylenia; MORENO-MATEOS , D.; FONT , M; PALOP , J. A.; JIM??NEZ RUIZ, Antonio; SANMART??N , Carmen; ."Selenocyanates and diselenides: a new class of potent antileishmanial agents". (ISSN: 0223-5234). European Journal of Medicinal Chemistry. 2011 , vol 8 , num 46 , p. 3315 - 3323

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• MORENO , D.; PLANO , D.; BAQUEDANO , Y.; JIM??NEZ RUIZ, Antonio; PALOP , J. A.; SANMART??N , C.; ."Antileishmanial activity of imidothiocarbamates and imidoselenocarbamates". (ISSN: 0932-0113). Parasitology Research. 2011 , vol 108 , num 1 , p. 233 - 239

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• TORO-LONDO??O , MIguel; PATI??O , Edwin Bairon; ROBLEDO , Sara Mar??a; JIM??NEZ RUIZ, Antonio; ALZATE , J.F.; ."Leishmania (Viannia) panamensis expresses a nuclease with molecular and biochemical features similar to the Endonuclease G of higher eukaryotes". Colombia M??dica. 2011 , num 42 , p. 154 - 165

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• SMIRLIS , P.; DUSZENKO , M.; JIM??NEZ RUIZ, Antonio; SCOULICA , E.; BASTIEN , P.; FASEL , N.; SOTERIADOU , K.; ."Targeting essential pathways in trypanosomatids gives insights into protozoan mechanisms of cell death". (ISSN: 1756-3305). PARASITES & VECTORS. 2010 , vol 3 , p. 107 - 107

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• JIM??NEZ RUIZ, Antonio; ALZATE , J.F.; MACLEOD , E.T.; LUDER , C.G.; FASEL , N.; HURD , H.; ."Apoptotic markers in protozoan parasites". (ISSN: 1756-3305). PARASITES & VECTORS. 2010 , vol 3 , num 1 , p. 104 - 104

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• NEGRI , A.; RODRIGUEZ-LARREA , D.; MARCO , E.; JIM??NEZ RUIZ, Antonio; SANCHEZ-RUIZ , J.M.; GAGO BADENAS, Federico; ."Protein-protein interactions at an enzyme-substrate interface: characterization of transient reaction intermediates throughout a full catalytic cycle of Escherichia coli thioredoxin reductase". (ISSN: 0887-3585). Proteins: Structure, Function and Genetics. 2010 , vol 78 , num 1 , p. 36 - 51

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• RICO , E.; ALZATE , J.F.; ARIAS , A.A.; MORENO-MATEOS , D.; CLOS , J.; GAGO BADENAS, Federico; MORENO , I.; DOMINGUEZ , M.; JIM??NEZ RUIZ, Antonio; ."Leishmania infantum expresses a mitochondrial nuclease homologous to EndoG that migrates to the nucleus in response to an apoptotic stimulus". (ISSN: 0166-6851). Molecular and Biochemical Parasitology. 2009 , vol 163 , num 1 , p. 28 - 38

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• ALZATE , J.F.; ARIAS , A.A.; MOLLINEDO , F.; RICO , E.; DE LA IGLESIA-VICENTE , J.; JIM??NEZ RUIZ, Antonio; ."Edelfosine induces an apoptotic process in Leishmania infantum that is regulated by the ectopic expression of Bcl-XL and Hrk". (ISSN: 0066-4804). Antimicrobial Agents and Chemotherapy. 2008 , vol 52 , num 10 , p. 3779 - 3792

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• ALZATE , J.F.; ARIAS , A.A.; MORENO-MATEOS , D.; BARRIENTOS , A.A.; JIM??NEZ RUIZ, Antonio; ."Mitochondrial superoxide mediates heat-induced apoptotic-like death in Leishmania infantum". (ISSN: 0166-6851). Molecular and Biochemical Parasitology. 2007 , vol 152 , num 2 , p. 192 - 202

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• ALZATE , J.F.; BARRIENTOS , A.A.; GONZ??LEZ , V.M.; JIM??NEZ RUIZ, Antonio; ."Heat-induced programmed cell death in Leishmania infantum is reverted by Bcl-X(L) expression". (ISSN: 1360-8185). Apoptosis : an international journal on programmed cell death. 2006 , vol 11 , num 2 , p. 161 - 171

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• ALZATE , J.F.; RAM??REZ-PINEDA , J.R.; GONZ??LEZ , V.M.; PATINO , E.; VELEZ , I.D.; JIM??NEZ RUIZ, Antonio; ."Leishmania (Viannia) Panamensis: Cloning of the Histone H1 genes by Representational Difference Analysis". (ISSN: 0014-4894). Experimental Parasitology. 2006 , vol 112 , num 2 , p. 126 - 129

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• KEDZIERSKI , L.; MONTGOMERY , J.; BULLEN , D.; CURTIS , J.; GARDINER , E.; JIM??NEZ RUIZ, Antonio; HANDMAN , E.; ."A Leucine-Rich Repeat Motif of Leishmania Parasite Surface Antigen 2 Binds to Macrophages through the Complement Receptor 3". (ISSN: 0022-1767). Journal of Immunology. 2004 , vol 172 , num 8 , p. 4902 - 4906

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• MORENO , M.; RINC??N , E.; PINEIRO , D.; FERNANDEZ , G.; DOMINGO GAL??N, Alberto; JIM??NEZ RUIZ, Antonio; SALINAS , M.; GONZ??LEZ , V.M.; ."Selection of aptamers against KMP-11 using colloidal gold during the SELEX process". (ISSN: 0006-291X). Biochemical and Biophysical Research Communications. 2003 , num 308 , p. 214 - 218

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• JIM??NEZ RUIZ, Antonio; ALV??REZ , N.; GONZ??LEZ , V.M.; ."Be careful with the primers when screening your clones by PCR". (ISSN: 0003-2697). Analytical Biochemistry. 2002 , num 308 , p. 189 - 191

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• PAREJA , J.C.; JIM??NEZ RUIZ, Antonio; ."Mapping 3' termini of mRNA on DNA templates with Taq-Polymerase 3' end labelled probes". (ISSN: 0003-2697). Analytical Biochemistry. 2000 , num 280 , p. 185 - 186

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• BOCETA , C.; ALONSO , C.; JIM??NEZ RUIZ, Antonio; ."Leucine rich repeats are the main epitopes in Leishmania infantum PSA during canine and human visceral leishmaniasis". (ISSN: 0141-9838). Parasite Immunology. 2000 , num 22(2) , p. 55 - 62

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• GONZ??LEZ , V.M.; FUERTES , M.A.; JIM??NEZ RUIZ, Antonio; ALONSO , C.; P??REZ , J.M.; ."The formation of DNA interstrand cross-links by a novel bis-[Pt2Cl4(diminazene aceturate)2]Cl4.4H2O complex inhibits the B to Z transition.". Molecular Pharmacology. 1999 , num 55 , p. 770 - 777

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• JIM??NEZ RUIZ, Antonio; BOCETA , C.; BONAY , P.; REQUENA , J.M.; ALONSO , C.; ."Cloning, sequencing and expression of the PSA genes from Leishmania infantum". (ISSN: 00142956). European Journal of Biochemistry. 1998 , num 251 , p. 389 - 397

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• BERBERICH , Christof; MACHADO , Gloria; MORALES , Gracia; CARRILLO , Graciela; JIM??NEZ RUIZ, Antonio; ALONSO , Carlos; ."The expression of the Leishmania infantum KMP-11 protein is developmentally regulated and stage specific". (ISSN: 0006-3002). Biochimica et Biophysica Acta. 1998 , num 1442 , p. 230 - 237

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• JIM??NEZ RUIZ, Antonio; BOCETA , C.; ALONSO , C.; ."El ant??geno de superficie PSA de Leishmania infantum. Un nuevo miembro de la familia de repeticiones ricas en Leucina.". (ISSN: 0004-2927). Ars Pharmaceutica. 1997 , num 38 , p. 295 - 303

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• JIM??NEZ RUIZ, Antonio; REQUENA , J.M.; ALONSO , C.; ."Estructura y funci??n del ADN en conformaci??n Z. ". Investigaci??n y Ciencia.. 1997 , p. 56 - 64

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• JIM??NEZ RUIZ, Antonio; ZHANG , Q.; SHEN , C.-K.J.; ."In vivo binding of trimethyl-psoralen detects DNA structural alterations associated with transcribing regions in the human ??-globin cluster". (ISSN: 00219258). Journal of biological chemistry (Print). 1995 , num 270 , p. 28978 - 28981

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• REQUENA , J.M.; JIM??NEZ RUIZ, Antonio; SOTO , M.; L??PEZ , M.C.; ALONSO , C.; ."Characterization of a highly repeated interspersed DNA sequence of Trypanosoma cruzi: its potential use in diagnosis and strain classification". (ISSN: 0166-6851). Molecular and Biochemical Parasitology. 1992 , num 51 , p. 271 - 280

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• JIM??NEZ RUIZ, Antonio; REQUENA , J.M.; SOTO , M.; ASSIEGO , R.; SANTAREN , J.F.; L??PEZ , M.C.; PATARROYO , M.E.; ALONSO , C.; ."Regulation of hsp70 expression in Trypanosoma cruzi by temperature and growth phase". (ISSN: 0166-6851). Molecular and Biochemical Parasitology. 1992 , num 53 , p. 201 - 211

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• JIM??NEZ RUIZ, Antonio; REQUENA , J.M.; L??PEZ , M.C.; ALONSO , C.; ."A potential Z‑DNA‑forming sequence is located between two transcription units alternatively expressed during development of Drosophila hydei". (ISSN: 0027-8424). Proceedings of the National Academy of Sciences of the United States of America. 1991 , num 88 , p. 31 - 35

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• P??REZ , J.M.; NAVARRO-RANNINGER , M.C.; REQUENA , J.M.; JIM??NEZ RUIZ, Antonio; PARRONDO , E.; CRACIUNESCU , D.; L??PEZ , M.C.; ALONSO , C.; ."DNA binding properties and antileukemic (L1210) activity of a Pt‑pentamidine complex". (ISSN: 0009-2797). Chemico-Biological Interactions. 1991 , num 77 , p. 341 - 345

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• SOTO , M.; REQUENA , J.M.; JIM??NEZ RUIZ, Antonio; ALONSO , C.; ."The mRNA coding for the nucleosomal protein H2A of Leishmania is polyadenylated and has stem‑loops at the 3' end". Nucleic Acids Research. 1991 , num 19 , p. 4554 - 4554

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• MORALES , G.; REQUENA , J.M.; JIM??NEZ RUIZ, Antonio; L??PEZ , M.C.; UGARTE , M.; ALONSO , C.; ."Sequence and expression of the Drosophila phenylalanine hydroxylase mRNA". Gene. 1990 , num 93 , p. 213 - 219

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• LARAN , E.; REQUENA , J.M.; JIM??NEZ RUIZ, Antonio; ALONSO , C.; ."Actual complexity of transcribing domains in Drosophila polytene chromosomes". Brotheria Gen??tica . 1990 , num 9 , p. 155 - 170

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• LARAN , E.; REQUENA , J.M.; JIM??NEZ RUIZ, Antonio; L??PEZ , M.C.; ALONSO , C.; ."The heat shock protein hsp70 binds in vivo to subregions 2‑48BC and 3‑58D of the polytene chromosomes of Drosophila hydei". (ISSN: 0009-5915). Chromosoma. 1990 , num 99 , p. 315 - 320

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• REQUENA , J.M.; L??PEZ , M.C.; JIM??NEZ RUIZ, Antonio; MORALES , G.; ALONSO , C.; ."Complete nucleotide sequence of the hsp70 gene of T. cruzi". Nucleic Acids Research.. 1989 , num 17 , p. 797 - 797

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• JIM??NEZ RUIZ, Antonio; REQUENA , J.M.; LANCILLOTTI , F.; MORALES , G.; L??PEZ , M.C.; ALONSO , C.; ."Molecular cloning of a Drosophila potential Z-DNA forming sequence hybridizing in situ to a developmentally regulated subdivision of the polytene chromosomes". Nucleic Acids Research. 1989 , num 26 , p. 4579 - 4588

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• REQUENA , J.M.; L??PEZ , M.C.; JIM??NEZ RUIZ, Antonio; DE LA TORRE , J.C.; ALONSO , C.; ."A head-to-tail tandem organization of hsp 70 genes in Trypanosoma cruzi". Nucleic Acids Research. 1988 , num 16 , p. 1393 - 1406

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Artículos Electrónicos

No existen datos en este apartado

Congresos

• JIM??NEZ RUIZ, Antonio; REVUELTO , Alejanddro; CAMARASA , Mar??a Jos??; GARC??A , Juan Carlos; CARRILES , Alejandra; GUTI??RREZ VI??AS, Kilian Jes??s; GUTIERREZ , Kilian; HERMOSO , Juan; CAMARASA RIUS, Mar??a Jos??; VEL??ZQUEZ , Sonsoles; ." Dimerization modulators of trypanothione reductase as innovative potent and selective Leishmanicidal agents. ". Congreso. Nacional. "19 Congreso de la SEQT. New Challenges in Drug Discovery". Vitoria-Gasteiz (2019 - 2019).

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• JIM??NEZ RUIZ, Antonio; REVUELTO , Alejandro; L??PEZ MART??N, I.; ZANDA , N.; LUCIO ORTEGA, H??ctor Elessar de; GAGO BADENAS, Federico; CAMARASA , Mar??a Jos??; VEL??ZQUEZ , Sonsoles; ."Towards more potent peptide dimerization inhibitors of TryR of Leishmania infantum: exploring neighbouring hydrophobic binding-sites". Encuentro. Internacional. "16th IBERIAN PEPTIDE MEETING. 4TH CHEMBIO GROUP MEETING. Barcelona (Espa??a)". Barcelona (2018 - 2018).

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• JIM??NEZ RUIZ, Antonio; ." A novel approach to inhibit trypanothione reductase in Trypanosomatids: Dimerization inhibitors" ". Congreso. Nacional. "41 Congreso de la Sociedad Espa??ola de Bioqu??mica y Biolog??a Molecular". Santander (10/09/2018 - 13/09/2018).

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• BRAVO GARC??A, Ana; JIM??NEZ RUIZ, Antonio; ."Caracterizaci??n estructural y funcional de la enzima Endonucleasa G de Leishmania infantum, factores que regulan su actividad nucleasa.". Congreso. Nacional. "41 Congreso de la SEBBM - Santander 2018". Santander (10/09/2018 - 13/09/2018).

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• JIM??NEZ RUIZ, Antonio; ."FIRST REPORTED POTENT IN VITRO ANTILEISHMANIALACTIVITY OF PEPTIDES THAT TARGET THE DIMER INTERFACE OF LEISHMANIA INFANTUM TRYPANOTHIONE". Congreso. Internacional. "VII EFMC International Symposium on Advances in Synthetic and Medicinal Chemistry Vienna, Austria | August 27-31, 2017". Viena "(Austria)". (27/08/2017 - 31/08/2017).

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• SANMART??N SALINA, Patricia; JIM??NEZ RUIZ, Antonio; GONZ??LEZ GUIJARRO, Luis Alberto; ."Estudio de la funci??n del IRS-4 en el eje Hipotal??mico Hep??tico". Congreso. Nacional. "II Congreso de Se??alizaci??n Celular, SECUAH 2017.". Alcala de Henares (14/03/2017 - 16/03/2017).

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• JIM??NEZ RUIZ, Antonio; ."Hydrocarbon-stapled peptides targeting the dimerization interface of Leishmania infantum trypanothione reductase". Congreso. Internacional. "MedChem 2013 anual one-day meeting on Medicinal Chemistry of KVCV and SRC. Constrained peptides and macrocycles-new opportunities for drug discovery". Beerse "(B??lgica)". (22/11/2013 - 22/11/2013).

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• JIM??NEZ RUIZ, Antonio; ."Inhibitions of protein-protein interactions in trypanothione reductase (TryR) of Leishmania infantum: an innovative strategy". Nacional. "XVII national meeting SEQT". Madrid (02/10/2013 - 04/10/2013).

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• JIM??NEZ RUIZ, Antonio; S??NCHEZ MURCIA, Pedro Alejandro; ."Apoptotic-like function of Leishmania p32 protein in Saccharomyces cerevisiae". Congreso. Nacional. "XXXVI Congreso de la SEBBM ". Madrid (03/09/2013 - 06/09/2013).

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• JIM??NEZ RUIZ, Antonio; S??NCHEZ MURCIA, Pedro Alejandro; ."Structure-based domain assignment in Leishmania infantum EndoG and characterization of a pH-dependent regulatory switch". Nacional. Madrid (03/09/2013 - 06/09/2013).

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• JIM??NEZ RUIZ, Antonio; ."Synthesis and biological evaluation of dimerization inhibitors of trypanothione reductase of Leishmania infantum". Nacional. "III SEQT summer school". Tres Cantos (25/07/2013 - 27/07/2013).

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• JIM??NEZ RUIZ, Antonio; ."Involvement of the n-terminal domain in the expression of leishmania iInfantum tyrosine aminotransferase". Congreso. Internacional. "FEMS2013 - 5th Congress of European Microbiologists". Leipzig "(Alemania)". (21/07/2013 - 25/07/2013).

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• JIM??NEZ RUIZ, Antonio; ."Disruptors of dimerization as inhibitors of Leishmania infantum trypanothione reductase". Congreso. Internacional. "Worldleish5". Porto Galinhas "(Brasil)". (13/05/2013 - 17/05/2013).

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• JIM??NEZ RUIZ, Antonio; ."Identification of a Leishmania Bax inhibitor-1-related protein involved in cell death regulation". Congreso. Internacional. "Worldleish5". Porto Galinhas "(Brasil)". (13/05/2013 - 17/05/2013).

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• JIM??NEZ RUIZ, Antonio; ."Leishmania infantum endonuclease G presents a self-inhibitor domain that regulates its activity". Congreso. Internacional. "Worldleish5". Porto Galinhas "(Brasil)". (13/05/2013 - 17/05/2013).

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• JIM??NEZ RUIZ, Antonio; ."Novel assay to assess dimer disruption of L. infantum trypanothione reductase by peptides and small molecules.". Congreso. Internacional. "Worldleish5". (13/05/2013 - 17/05/2013).

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• BAQUEDANO , Ylenia; DOM??NGUEZ , Enrique; PLANO , Daniel; FONT , Maria; PALOP , Juan Antonio; JIM??NEZ RUIZ, Antonio; SANMART??N , Carmen; ."Design, synthesis and biological evaluation of new diselenide compounds as antileishmanial agents". Congreso. Internacional. "EFMC/ISMC CONGRESS". Berlin "(Alemania)". (02/09/2012 - 06/09/2012).

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• ROMANO , Beatriz; LAMBERTO , Iranzu; BAQUEDANO , Ylenia; IB????EZ , Elena; CALVO , Alfonso; JIM??NEZ RUIZ, Antonio; PALOP , Juan Antonio; SANMART??N , Carmen; ."Novel selenocarbamatoes as antiproliferative and antileishmanial agents". Congreso. Internacional. "EFMC/ISMC CONGRESS". Berlin "(Alemania)". (02/09/2012 - 06/09/2012).

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• BAQUEDANO , Ylenia; D??AZ , Marta; LAMBERTO , Iranzu; DOM??NGUEZ , Enrique; JIM??NEZ RUIZ, Antonio; PALOP , Juan Antonio; SANMART??N , Carmen; ."Novel sulfonamides: a new class of potent antileishmanial agents". Congreso. Internacional. "EFMC/ISMC 2012 Congress". Berlin "(Alemania)". (02/09/2012 - 06/09/2012).

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• BUEREN CALABUIG, Juan Antonio; RICO VIDAL, Eva; OLIVA CORREIA, Cristina; JIM??NEZ RUIZ, Antonio; GAGO BADENAS, Federico; ."Structural insights into Leishmania infantum endoG active site and analysis of the reaction mechanism ". Congreso. Internacional. "Second Iberic Meeting on Medicinal Chemistry: G rotein-Coupled Receptors and Enzymes in Drug Discovery ". Oporto "(Portugal)". (12/06/2011 - 15/06/2011).

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• JIM??NEZ RUIZ, Antonio; ."International Training School". Workshop. Internacional. Alcala de Henares (13/09/2010 - 18/09/2010).

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• JIM??NEZ RUIZ, Antonio; ." Muerte celular programada en el par??sito protozoo Leishmania infantum: caracter??sticas del proceso y mol??culas implicadas". Congreso. Nacional. "XIV Congreso Colombiano de Parasitolog??a y Medicina Tropical". Medell??n "(Colombia)". (08/10/2009 - 11/10/2009).

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• MORENO-MATEOS , D.; ARIAS , A.A.; ALZATE , J.F.; JIM??NEZ RUIZ, Antonio; ." Characaterizatin o the cell death process induced by ebselen in Leishmania infantum.". Congreso. Internacional. "WorldLeish 4". Lucknow "(India)". (03/02/2009 - 07/02/2009).

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• RICO , E.; ALZATE , J.F.; MORENO , D.; BUEREN , J.; GAGO BADENAS, Federico; JIM??NEZ RUIZ, Antonio; ." Structural and functional analysis of Leishmania infantum EndoG". Congreso. Internacional. "WorldLeish 4". Lucknow "(India)". (03/02/2009 - 07/02/2009).

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• MORENO-MATEOS , D.; RICO , E.; ALZATE , J.F.; ARIAS , A.A.; CLOS , J.; GAGO BADENAS, Federico; JIM??NEZ RUIZ, Antonio; ." Conservation of an endonuclease G like protein in Leishmania infantum.". Congreso. Internacional. "Molecular Parasitology Meeting XIX". Woodshole "(Estados Unidos)". (21/09/2008 - 25/09/2008).

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• RICO , E.; ALZATE , J.F.; MORENO , D.; ARIAS , A.A.; CLOS , J.; GAGO BADENAS, Federico; JIM??NEZ RUIZ, Antonio; ." L. Infantum mitochondrion contains a nuclease homologous to EndoG that migrates to the nucleus in response to an apoptotic stimulus". Congreso. Internacional. Woodshole "(Estados Unidos)". (21/09/2008 - 25/09/2008).

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• ALZATE , J.F.; ALVAREZ BARRIENTOS , A.; GONZALEZ , V.M.; JIM??NEZ RUIZ, Antonio; ."Analysis of the heat-induced cell death in Leishmania by flow-cytometry". Internacional. "Worldleish 3". "(Italia)". (10/04/2005 - ).

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• DEL ALAMO , M.; P??REZ , A; CALVO , M.; JIM??NEZ RUIZ, Antonio; GONZ??LEZ , V.M.; ALONSO , C.; DELGADO-IRIBARREN , A.; ."Evaluation of recombinant antigens and commercial assays for the diagnosis of Leishmaniasis". Conferencia. Internacional. "XXXVIII INTERSCIENCE CONFERENCE ON ANTIMICROBIAL AGENTS AND CHEMOTHHERAPY". San Diego "(Estados Unidos)". (09/1998 - ).

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• REQUENA , J.M.; JIM??NEZ RUIZ, Antonio; L??PEZ , M.C.; ALONSO , C.; ."Chromosomal Regi??n 4?75C2 of D.hydei contains a cloned Z?forming sequence and it is in a transient B? to Z?DNA flux in vivo during development". Internacional. "Workshop on "Chromatine Structure and Gene Expression"". "(Espa??a)". (24/09/1990 - 26/09/1990).

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• REQUENA , J.M.; JIM??NEZ RUIZ, Antonio; LARAN , E.; L??PEZ , M.C.; ALONSO , C.; ."Hsp 70 binds in vivo to subregions 2?48BC and 3?58D of the Polytene chromosomes of Drosophila hydei.". Internacional. "Workshop on Heatshock". Ravello "(Italia)". (17/09/1990 - 20/09/1990).

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• P??REZ , J.M.; REQUENA , J.M.; JIM??NEZ RUIZ, Antonio; L??PEZ , M.C.; ALONSO , C.; ."An??lisis Bioqu??mico y Estructural del an??logo de Platino: cis?dicloro (pentamidina) Platino III". Nacional. "XVI Congreso Nacional de Bioqu??mica". "(Espa??a)". (10/1989 - 31/10/1989).

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• REQUENA , J.M.; JIM??NEZ RUIZ, Antonio; MORALES , G.; ALONSO , C.; ."Clonaje de un gen inducible por ecdisona en la regi??n 4?75C de D.hydei.". Nacional. "XVI Congreso Nacional de Bioqu??mica". "(Espa??a)". (10/1989 - 31/10/1989).

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• REQUENA , J.M.; JIM??NEZ RUIZ, Antonio; MORALES , G.; L??PEZ , M.C.; ALONSO , C.; ."Secuencias formadoras de Z?DNA en Drosophila hydei". Europeo. "III Congreso Luso Espa??ol de Bioqu??mica". "(Espa??a)". (09/1988 - 30/09/1988).

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Tesis

• OLIVA CORREIA, Cristina; "Caracterizaci??n funcional y estructural de la endonucleasa G de Leishmania infantum. Exploraci??n de su potencial como diana para el desarrollo de agentes terap??uticos con actividad leishmanicida.". Director: JIM??NEZ RUIZ, Antonio, GAGO BADENAS, Federico, . UNIVERSIDAD DE ALCALA. Fecha de lectura: 28/07/2020. Sobresaliente cum laude.

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• LUCIO ORTEGA, H??ctor Elessar de; "Inhibici??n de la tripanoti??n reductasa de Leishmania infantum mediada por peptidomim??ticos de la h??lice Alpha2 de la interfaz de dimerizaci??n". Director: JIM??NEZ RUIZ, Antonio, GAGO BADENAS, Federico, . UNIVERSIDAD DE ALCALA. Fecha de lectura: 02/11/2018. Sobresaliente cum laude.

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• TORO LONDO??O, Miguel ??ngel; "Dise??o y evaluaci??n de inhbidores pept??dicos dirigidos a la interfaz de dimerizaci??n de la tripanoti??n reductasa de Leishmania infantum". Director: JIM??NEZ RUIZ, Antonio, GAGO BADENAS, Federico, . UNIVERSIDAD DE ALCALA. Fecha de lectura: 30/06/2017. Sobresaliente cum laude.

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• GENES ROBLES, Carlos Mario; "Muerte celular similar a apoptosis en Leishmania spp: una aproximaci??kn a su regulaci??n". Director: JIM??NEZ RUIZ, Antonio, . UNIVERSIDAD DE ALCALA. Fecha de lectura: 19/07/2013. sobresaliente cum laude.

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• RICO VIDAL, Eva; "Estudio de la nucleasa EndoG en el protozoo Leishmania infantum: caracterizaci??n e implicaciones en la supervivencia y muerte del par??sito". Director: JIM??NEZ RUIZ, Antonio, GAGO BADENAS, Federico, . Mención Europea . UNIVERSIDAD DE ALCALA. Fecha de lectura: 15/11/2010. Sobresaliente cum laude.

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• MORENO MATEOS, David; "Estrategias celulares y moleculares en el cribado de nuevos agentes anti-Leishmania". Director: JIM??NEZ RUIZ, Antonio, GAGO BADENAS, Federico, . UNIVERSIDAD DE ALCALA. Fecha de lectura: 24/07/2010. Sobresaliente cum laude.

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